The importance of a positive family history for the predisposition to coronary heart disease and myocardial infarction is well established. Erdmann J. et al. describe in their just published Nature article how two seperate mutations in two functional relates genes directly lead to accelerated thrombus formation in the microcirculation. The mutations have been found in a large german family out of which 23 had suffered of a myocardial infarction. Is the answer for further improvement in the treatment of myocardial infarctions maybe in our genes...?
Erdmann J. et al. Nature, November 2013; nature 12722